Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 8/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5810683 | 0.73 | TSHR (0.36) | IDH1 | |
| SCHEMBL5775170 | 0.72 | COMT (0.36) | IDH1 | |
| SCHEMBL5775618 | 0.69 | KMO (0.47) | PDE3BPDE3AIDH1 | |
| SCHEMBL6848865 | 0.68 | PARP1 (0.35) | CECR2PARP1PDE3BPDE3AHTR1A | |
| SCHEMBL6848824 | 0.68 | PARP1 (0.35) | CECR2PARP1PDE3BPDE3AHTR1A | |
| SCHEMBL5775925 | 0.67 | NR3C2 (0.43) | PARP1 | |
| SCHEMBL5773816 | 0.66 | BRD4 (0.39) | PDE3BPDE3AIDH1BRD4 | |
| SCHEMBL7000081 | 0.66 | PARP1 (0.55) | PARP1PDE3BPDE3ASMYD3 | |
| SCHEMBL531642 | 0.65 | PARP1 (0.46) | CECR2PARP1PDE3BPDE3ASMYD3 | |
| SCHEMBL5775116 | 0.65 | HSD11B1 (0.47) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472348-B1 | Pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2002-10-29 | — | — | US | disclosed |
| US-6265349-B1 | Pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD (JP) | 2001-07-24 | — | — | US | disclosed |
| US-6048823-A | Pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0885885-A1 | PYRIDONE DERIVATIVES AND HERBICIDES | KumaiI Chemical Industry Co., Ltd. (JP) | 1998-12-23 | — | — | EP | disclosed |