Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1365999 | 0.73 | CES2 (0.37) | CHRNA7 | |
| SCHEMBL12490653 | 0.69 | CYP2A6 (0.41) | CHRNA7 | |
| SCHEMBL18003338 | 0.66 | ALDH1A1 (0.35) | CHRNA7 | |
| SCHEMBL23106378 | 0.66 | CHRNA7 (0.33) | CHRNA7 | |
| SCHEMBL12490263 | 0.65 | CYP2A6 (0.41) | CHRNA7 | |
| SCHEMBL2898184 | 0.64 | GPR35 (0.48) | CHRNA7MAPK14 | |
| SCHEMBL5230123 | 0.60 | CHRNA7 (0.38) | CHRNA7 | |
| SCHEMBL3298107 | 0.59 | IDO1 (0.58) | GPR84MAPK14 | |
| SCHEMBL15896593 | 0.56 | DAO (0.35) | — | |
| SCHEMBL2091126 | 0.55 | GPR84 (0.38) | GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006132947-A2 | 3-ACYL COUMARINS, THIOCHROMONES AND QUINOLONES AND THERAPEUTIC USES THEREOF | TEMPLE UNIVERSITY- OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2006-12-14 | — | — | WO | claimed |