Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797682 | 0.89 | GCGR (0.46) | NPC1RAB9APIN1KMT2AMEN1 | |
| SCHEMBL5822007 | 0.86 | PIN1 (0.44) | PIN1KMT2AMEN1DAPK1PIM3 | |
| SCHEMBL5813652 | 0.85 | MEN1 (0.50) | PIN1KMT2AMEN1DAPK1PIM3 | |
| SCHEMBL5799682 | 0.84 | NPC1 (0.39) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5824029 | 0.83 | ALDH1A1 (0.45) | NPC1RAB9AKMT2AMEN1DAPK1 | |
| SCHEMBL5796113 | 0.82 | ALDH1A1 (0.43) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5807764 | 0.82 | GCGR (0.46) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5807771 | 0.82 | GCGR (0.46) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5796112 | 0.82 | ALDH1A1 (0.43) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5809477 | 0.82 | MAPK1 (0.41) | NPC1RAB9AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |