SCHEMBL5813089

SCHEMBL5813089

CCCOC(=O)CCNC(C)=O

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
GLA P06280 1/20 0.44
DGKA P23743 1/20 0.44
TOP2A P11388 2/20 0.43
PAOX Q6QHF9 1/20 0.42
KDM4E B2RXH2 1/20 0.41
MAPK1 P28482 1/20 0.41
HIF1A Q16665 1/20 0.41
EPHX2 P34913 1/20 0.41
ACACB O00763 1/20 0.41
MTNR1A P48039 2/20 0.41
MTNR1B P49286 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
TSHR P16473 1/20 0.39
ADRA1A P35348 2/20 0.38
ACHE P22303 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ADRA2A P08913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5812715 0.89 DGKA (0.50) DGKATOP2APAOXKDM4EMAPK1
SCHEMBL2027274 0.89 ALDH1A1 (0.50) ALDH1A1DGKAPAOXKDM4EMAPK1
SCHEMBL26009556 0.88 MTNR1A (0.47) ALDH1A1DGKAPAOXKDM4EMAPK1
SCHEMBL6343479 0.85 NAAA (0.56) DGKAEPHX2TSHRACHE
SCHEMBL11679450 0.85 NAAA (0.56) DGKAEPHX2TSHRACHE
SCHEMBL11673997 0.85 NAAA (0.56) DGKAEPHX2TSHRACHE
SCHEMBL11675793 0.85 NAAA (0.56) DGKAEPHX2TSHRACHE
SCHEMBL25845061 0.84 ALDH1A1 (0.46) ALDH1A1DGKAPAOXKDM4EMAPK1
SCHEMBL48439 0.83 GAA (0.52) ALDH1A1TOP2APAOXKDM4EMAPK1
SCHEMBL14902254 0.83 ALDH1A1 (0.41) ALDH1A1GLADGKATOP2AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006119283-A2 ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE YU RUEY J (US) 2006-11-09 WO claimed
US-20060251597-A1 ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE YU RUEY J 2006-11-09 US claimed
US-20060251597-A1 ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE YU RUEY J 2006-11-09 US disclosed