SCHEMBL5813102

SCHEMBL5813102

CCCCCCCCCCCCCCCC(F)F

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.52
TSHR P16473 1/20 0.50
THRB P10828 1/20 0.50
LMNA P02545 1/20 0.48
DNM1 Q05193 2/20 0.48
OPRM1 P35372 1/20 0.46
GPR84 Q9NQS5 3/20 0.42
FDPS P14324 3/20 0.42
SPHK1 Q9NYA1 1/20 0.42
FFAR1 O14842 1/20 0.42
CES2 O00748 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16933738 1.00 MAPT (0.52) MAPTTSHRTHRBLMNADNM1
SCHEMBL45607 1.00 MAPT (0.52) MAPTTSHRTHRBLMNADNM1
SCHEMBL3366534 1.00
SCHEMBL16933754 1.00 MAPT (0.52) MAPTTSHRTHRBLMNADNM1
SCHEMBL18955394 1.00 MAPT (0.52) MAPTTSHRTHRBLMNADNM1
SCHEMBL3362398 1.00 MAPT (0.52) MAPTTSHRTHRBLMNADNM1
SCHEMBL45648 1.00 MAPT (0.52) MAPTTSHRTHRBLMNADNM1
SCHEMBL16933949 1.00 MAPT (0.52) MAPTTSHRTHRBLMNADNM1
SCHEMBL16934254 1.00 MAPT (0.52) MAPTTSHRTHRBLMNADNM1
SCHEMBL10548954 1.00 MAPT (0.52) MAPTTSHRTHRBLMNADNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017100514-A1 LIPOPHILIC ANALOGS OF CJ-16264, METHODS OF USE, AND SYNTHESIS THEREOF WILLIAM MARSH RICE UNIVERSITY (US) 2017-06-15 WO claimed
EP-3527600-B1 ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-09 EP disclosed
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-04-13 US disclosed
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-01-10 US disclosed
WO-2022263927-A2 PLASMALOGEN DERIVATIVES AND USES THEREOF PHOSKA BIOPHARMA PTE. LTD. (SG) 2022-12-22 WO disclosed
CN-109803992-B Isocyanate composition and method for producing isocyanate polymer 旭化成株式会社 2022-05-24 CN disclosed
CN-109843963-B Isocyanate composition, method for producing isocyanate polymer, and isocyanate polymer 旭化成株式会社 2022-05-13 CN disclosed
EP-3536683-B1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION ASAHI CHEMICAL IND (JP) 2021-11-24 EP disclosed
US-11174337-B2 Isocyanate composition, method for producing isocyanate polymer and isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-11-16 US disclosed
CN-107963982-B Polyisocyanate composition and isocyanate polymer composition 旭化成株式会社 2021-11-12 CN disclosed
US-10301417-B2 Polyisocyanate composition and isocyanate polymer composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2019-05-28 US disclosed
US-10125212-B2 Polyisocyanate composition and isocyanate polymer composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-11-13 US disclosed
EP-3372579-A1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2018-09-12 EP disclosed
US-20170298169-A1 Polyisocyanate Composition and Isocyanate Polymer Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2017-10-19 US disclosed
WO-2017100514-A1 LIPOPHILIC ANALOGS OF CJ-16264, METHODS OF USE, AND SYNTHESIS THEREOF WILLIAM MARSH RICE UNIVERSITY (US) 2017-06-15 WO disclosed
EP-2915803-A1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2015-09-09 EP disclosed
US-20150210631-A1 Polyisocyanate Composition and Isocyanate Polymer Composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2015-07-30 US disclosed
US-20140338750-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT Konica Minolta, Inc. (JP) 2014-11-20 US disclosed
US-20060288929-A1 Polar surface preparation of nitride substrates CRYSTAL IS, INC. (US) 2006-12-28 US disclosed
WO-2006135688-A2 POLAR SURFACE PREPARATION OF NITRIDE SUBSTRATES CRYSTAL IS, INC. (US) 2006-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10301417-B2 Polyisocyanate composition and isocyanate polymer composition PAH, ALKBH1, ALKBH3 MAPT 1300/4885TSHR 4682/4885THRB 4174/4885
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer IDH3A, IDH2, IDH3B MAPT 1287/4885TSHR 4885/4885THRB 4881/4885
US-20170298169-A1 Polyisocyanate Composition and Isocyanate Polymer Composition TST, SUDS3, SCLY MAPT 2554/4885TSHR 4448/4885THRB 4301/4885
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER IDH3A, IDH2, IDH3B MAPT 1045/4885TSHR 4885/4885THRB 4879/4885
US-10125212-B2 Polyisocyanate composition and isocyanate polymer composition TST, SUDS3, SCLY MAPT 2554/4885TSHR 4448/4885THRB 4301/4885
US-20150210631-A1 Polyisocyanate Composition and Isocyanate Polymer Composition TST, SUDS3, SCLY MAPT 2554/4885TSHR 4448/4885THRB 4301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.