SCHEMBL5813461

SCHEMBL5813461

O=C(O)C(Cc1ccc(F)c(F)c1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 2/20 0.51
PPARG P37231 4/20 0.45
PPARA Q07869 4/20 0.45
DPP4 P27487 2/20 0.44
PIN1 Q13526 1/20 0.44
DPP7 Q9UHL4 1/20 0.43
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
KDM6B O15054 1/20 0.42
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
MDM2 Q00987 1/20 0.41
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
EGFR P00533 1/20 0.41
LCK P06239 1/20 0.41
FYN P06241 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
ALOX15 P16050 1/20 0.41
PTGS1 P23219 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7230282 0.85 KDM6B (0.61) PPARGPPARADPP4PIN1DPP7
SCHEMBL7711037 0.85 KDM6B (0.61) PPARGPPARADPP4PIN1DPP7
SCHEMBL18511382 0.83 SLC7A5 (0.62) KDM4EUSP2EGFRLCKFYN
SCHEMBL1613644 0.83 SLC7A5 (0.62) KDM4EUSP2EGFRLCKFYN
SCHEMBL6003677 0.83 TBXAS1 (0.44) PPARADPP4PIN1MAOAMAOB
SCHEMBL44052 0.83 SLC7A5 (0.62) KDM4EUSP2EGFRLCKFYN
SCHEMBL17336531 0.83 LDHA (0.47) LDHAPPARGPPARAKDM6BKDM4E
SCHEMBL6005325 0.83 TBXAS1 (0.44) PPARADPP4PIN1MAOAMAOB
SCHEMBL6003686 0.83 TBXAS1 (0.44) PPARADPP4PIN1MAOAMAOB
SCHEMBL44051 0.83 SLC7A5 (0.62) KDM4EUSP2EGFRLCKFYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006136327-A1 FUNGICIDAL BENZYLPYRIMIDINE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2006-12-28 WO disclosed