Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 9/20 | 0.60 |
| ▸ | CNR1 | P21554 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804272 | 0.79 | NTRK1 (0.62) | NTRK1ALDH1A1POLBGAAKDM4E | |
| SCHEMBL16595137 | 0.77 | NTRK1 (1.00) | NTRK1ALDH1A1POLBGAAKDM4E | |
| SCHEMBL5815917 | 0.77 | NTRK1 (0.65) | NTRK1ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL10568558 | 0.76 | GAA (0.45) | CNR1ALDH1A1GAA | |
| SCHEMBL5804820 | 0.74 | NTRK1 (0.58) | NTRK1ALDH1A1POLBGAAKDM4E | |
| SCHEMBL8252821 | 0.73 | NTRK1 (0.60) | NTRK1ALDH1A1GAAPTGS2 | |
| SCHEMBL8259077 | 0.73 | NTRK1 (0.71) | NTRK1ALDH1A1POLBGAAKDM4E | |
| SCHEMBL5814359 | 0.73 | NTRK1 (0.85) | NTRK1ALDH1A1POLBGAAKDM4E | |
| SCHEMBL5804817 | 0.73 | NTRK1 (0.59) | NTRK1ALDH1A1POLBGAAKDM4E | |
| SCHEMBL11648787 | 0.72 | NTRK1 (0.89) | NTRK1ALDH1A1POLBGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006085815-A1 | THIAZOLE DERIVATIVES, THEIR PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY | ASTRAZENECA AB (SE) | 2006-08-17 | — | — | WO | disclosed |