Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820276 | 0.89 | PTGDR2 (0.65) | EGFRERBB2PTGDR2GAAMAPT | |
| SCHEMBL5819527 | 0.86 | GAA (0.47) | PTGDR2GAAMAPT | |
| SCHEMBL5815533 | 0.83 | PTGDR2 (0.69) | EGFRERBB2PTGDR2GAAMAPT | |
| SCHEMBL5820644 | 0.79 | EGFR (0.53) | EGFRERBB2 | |
| SCHEMBL5544242 | 0.78 | PTGDR2 (0.76) | PTGDR2GAAMAPT | |
| SCHEMBL348219 | 0.72 | AR (0.48) | EGFRERBB2PTGDR2GAAMAPT | |
| Trifluoroacetic Acid SCHEMBL4092194 | 0.70 | AR (0.44) | EGFRERBB2PTGDR2GAAMAPT | |
| SCHEMBL13997494 | 0.70 | TRPM8 (0.62) | PTGDR2GAAMAPT | |
| SCHEMBL28616617 | 0.69 | CYP1A2 (0.49) | PTGDR2GAAMAPT | |
| SCHEMBL5815917 | 0.69 | NTRK1 (0.65) | PTGDR2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006085815-A1 | THIAZOLE DERIVATIVES, THEIR PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY | ASTRAZENECA AB (SE) | 2006-08-17 | — | — | WO | disclosed |
| WO-2006085815-A1 | THIAZOLE DERIVATIVES, THEIR PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY | ASTRAZENECA AB (SE) | 2006-08-17 | — | — | WO | disclosed |