Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAT2A | P31153 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5816427 | 0.84 | GRM2 (0.35) | SYKKDM5AALDH1A1KDM4EMAPT | |
| SCHEMBL4788702 | 0.82 | GRM2 (0.36) | KDM5AKDM4EMAPTMAPK1HSD17B10 | |
| SCHEMBL5814919 | 0.81 | KDM5A (0.33) | KDM5AALDH1A1KDM4EMAPTHTT | |
| SCHEMBL4747371 | 0.80 | NPC1 (0.34) | SYKALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL4747891 | 0.80 | SYK (0.39) | SYKALDH1A1KDM4EMAPTMAT2A | |
| SCHEMBL5820088 | 0.80 | SYK (0.39) | SYKALDH1A1KDM4EMAPTMAT2A | |
| SCHEMBL4749987 | 0.77 | EGFR (0.42) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL4750208 | 0.77 | JAK2 (0.43) | KDM5AALDH1A1KDM4EMAPTMAT2A | |
| SCHEMBL17986898 | 0.67 | HRH4 (0.42) | SYKMAPTNPY5R | |
| SCHEMBL4747717 | 0.66 | GRM2 (0.36) | SYKALDH1A1KDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006112666-A1 | PYRIDINE DERIVATIVES, METHODS OF THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SK CHEMICALS CO., LTD. (KR) | 2006-10-26 | — | — | WO | claimed |
| WO-2006112666-A1 | PYRIDINE DERIVATIVES, METHODS OF THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SK CHEMICALS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |