SCHEMBL6911920

SCHEMBL6911920

CC(=O)CCS(=O)(=O)c1ccccc1C

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.54
HTT P42858 3/20 0.54
KEAP1 Q14145 1/20 0.48
NFE2L2 Q16236 1/20 0.48
KMT2A Q03164 5/20 0.47
MEN1 O00255 4/20 0.47
GAA P10253 2/20 0.47
LMNA P02545 1/20 0.47
POLB P06746 4/20 0.46
MAPT P10636 3/20 0.46
APEX1 P27695 1/20 0.46
ALOX12 P18054 1/20 0.43
HPGD P15428 2/20 0.41
TP53 P04637 1/20 0.41
GRK2 P25098 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10514057 0.86 APEX1 (0.64) ALDH1A1HTTKEAP1NFE2L2KMT2A
SCHEMBL7194392 0.82 KEAP1 (0.57) ALDH1A1HTTKEAP1NFE2L2KMT2A
SCHEMBL581476 0.81 ALDH1A1 (0.46) ALDH1A1HTTKEAP1NFE2L2KMT2A
SCHEMBL28192514 0.80 LMNA (0.48) ALDH1A1HTTKEAP1NFE2L2KMT2A
SCHEMBL5763362 0.79 KEAP1 (0.51) ALDH1A1HTTKEAP1NFE2L2KMT2A
SCHEMBL11692985 0.79 KEAP1 (0.46) ALDH1A1HTTKEAP1NFE2L2KMT2A
Hydrazine SCHEMBL28015266 0.79 ALDH1A1 (0.43) ALDH1A1HTTKEAP1NFE2L2KMT2A
SCHEMBL6097634 0.77 KEAP1 (0.53) ALDH1A1HTTKEAP1NFE2L2KMT2A
SCHEMBL6667757 0.76 L3MBTL1 (0.47) ALDH1A1HTTKEAP1NFE2L2KMT2A
SCHEMBL9673270 0.76 KEAP1 (0.52) ALDH1A1HTTKEAP1NFE2L2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6727294-B2 RADIATION TRANSPARENT MOLDING MATERIALS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-04-27 US disclosed
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
EP-0753540-B1 Polycarbonate resin composition MITSUBISHI ENG PLASTICS CORP (JP) 2003-06-11 EP disclosed
US-6359028-B1 USED IN MEDICAL EQUIPMENT, DISCOLORATION INHIBITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2002-03-19 US disclosed
US-20010034419-A1 Radiation transparent molding materials MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2001-10-25 US disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5977206-A Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-11-02 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed