Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK6 | Q92876 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5428767 | 0.89 | MAPT (0.53) | KLK6TSHRPOLBMAPTALDH1A1 | |
| SCHEMBL5425614 | 0.88 | MAPT (0.57) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5429451 | 0.81 | TSHR (0.61) | TSHRPOLBMAPTALDH1A1LMNA | |
| SCHEMBL5431770 | 0.81 | NPC1 (0.60) | TSHRPOLBMAPTALDH1A1MEN1 | |
| SCHEMBL31218207 | 0.74 | HRH3 (0.67) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7807900 | 0.74 | HRH3 (0.67) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8889137 | 0.73 | MAPT (0.65) | CYP1A2POLBCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL18229442 | 0.73 | HRH3 (0.69) | CYP1A2POLBCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1853622 | 0.72 | LMNA (0.71) | MAPTALDH1A1PKMHTTMEN1 | |
| SCHEMBL28373040 | 0.72 | MAPT (0.65) | CYP1A2POLBCYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185115-A1 | Novel ureido-and amido-pyrazolone derivatives | ASTON UNIVERSITY (GB) | 2007-08-09 | — | — | US | disclosed |
| US-20070185115-A1 | Novel ureido-and amido-pyrazolone derivatives | ASTON UNIVERSITY (GB) | 2007-08-09 | — | — | US | disclosed |
| EP-1628963-A1 | NOVEL UREIDO - AND AMIDO-PYRAZOLONE DERIVATIVES | Aston University (GB) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004106306-A1 | NOVEL UREIDO - AND AMIDO-PYRAZOLONE DERIVATIVES | ASTON UNIVERSITY (GB) | 2004-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185115-A1 | Novel ureido-and amido-pyrazolone derivatives | CCKAR, CCKBR, GRPR | KLK6 3070/4885TSHR 116/4885CYP1A2 2612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.