Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.60 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.60 |
| ▸ | TUBB | P07437 | 7/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.60 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.60 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.60 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.60 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5840652 | 0.85 | CCNB2 (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5840646 | 0.85 | CCNB2 (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11014243 | 0.82 | ATM (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5817386 | 0.82 | TUBB1 (0.74) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5839385 | 0.77 | PAX8 (0.44) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5839375 | 0.77 | PAX8 (0.44) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Colchinol SCHEMBL29915223 | 0.75 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Flavanthridin SCHEMBL28245579 | 0.74 | TUBB1 (0.53) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Ephemeranthol A SCHEMBL28598214 | 0.74 | TUBB4A (0.53) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL353879 | 0.71 | HTT (0.47) | KDM4ECYP3A4ALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006067412-A1 | CHEMICAL PROCESSES FOR THE PREPARATION OF A COLCHINOL DERIVATIVE AND INTERMEDIATES | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |