Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.47 |
| ▸ | TUBB | P07437 | 7/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5840646 | 0.82 | CCNB2 (0.51) | ATMTDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL5840652 | 0.82 | CCNB2 (0.51) | ATMTDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL5815215 | 0.82 | TUBB1 (0.60) | TDP1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5839375 | 0.77 | PAX8 (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5839385 | 0.77 | PAX8 (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3411050 | 0.77 | PTGS2 (0.39) | TDP1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL4114766 | 0.77 | PTGS2 (0.39) | TDP1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL7445824 | 0.76 | ATM (0.63) | ATMTDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL11356640 | 0.74 | ATM (0.66) | ATMTDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL6378725 | 0.74 | TUBB4A (0.66) | ATMTDP1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144235-A2 | N6-(1- and 2-benzocycloalkyl) adenosines, pharmaceutical compositions comprising the same and a process for the production thereof | WARNER-LAMBERT COMPANY (US) | 1985-06-12 | — | — | EP | disclosed |