Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5817016 | 0.89 | L3MBTL1 (0.47) | L3MBTL1NPC1RAB9AGLAOPRM1 | |
| SCHEMBL5816696 | 0.84 | MEN1 (0.46) | NPC1MEN1KMT2ACYP2C19IDO1 | |
| SCHEMBL5820957 | 0.80 | TP53 (0.46) | NPC1RAB9AMEN1KMT2ACYP2C19 | |
| SCHEMBL5820384 | 0.79 | LMNA (0.47) | L3MBTL1NPC1RAB9AGLAMEN1 | |
| SCHEMBL5817048 | 0.76 | L3MBTL1 (0.52) | L3MBTL1NPC1RAB9AGLACYP2C19 | |
| SCHEMBL5814485 | 0.75 | SMN1; SMN2 (0.53) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5816762 | 0.74 | ALDH1A1 (0.43) | L3MBTL1NPC1MEN1KMT2ACYP2C19 | |
| SCHEMBL13114758 | 0.70 | MAPT (0.47) | NPC1RAB9AGLAMEN1KMT2A | |
| SCHEMBL7658070 | 0.70 | NPC1 (0.44) | L3MBTL1NPC1RAB9A | |
| SCHEMBL5819589 | 0.68 | SRC (0.53) | NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117657-A1 | TRIAZOLONE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2006-11-09 | — | — | WO | disclosed |