SCHEMBL5815286

SCHEMBL5815286

CCCC/C=C/N1CCN(/C=C/CCCC)C1=O

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.38
MGLL Q99685 3/20 0.38
TSHR P16473 3/20 0.35
ALDH1A1 P00352 2/20 0.35
TRPV1 Q8NER1 1/20 0.33
F7 P08709 1/20 0.33
F3 P13726 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5815289 1.00 FAAH (0.38) FAAHMGLLTSHRALDH1A1TRPV1
SCHEMBL5802377 0.81 FAAH (0.42) FAAHMGLLTSHRTRPV1F7
SCHEMBL5814341 0.78 MGLL (0.41) FAAHMGLLTSHR
SCHEMBL7793970 0.78 MGLL (0.41) FAAHMGLLTSHR
SCHEMBL7059780 0.78 MGLL (0.41) FAAHMGLLTSHR
SCHEMBL5799752 0.77 NAAA (0.43) FAAHMGLLTSHRALDH1A1
SCHEMBL5800684 0.75 FAAH (0.39) FAAHMGLL
SCHEMBL7794085 0.73 FAAH (0.46) FAAHMGLLTRPV1
SCHEMBL7794084 0.73 FAAH (0.46) FAAHMGLLTRPV1
SCHEMBL2543005 0.72 MGLL (0.39) FAAHMGLLTSHRALDH1A1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006056166-A2 METHOD FOR THE ADDITION OF AMIDES UREAS LACTAMS AND CARBAMATES TO ALKYNES STUDIENGESELLSCHAFT KOHLE MBH (DE) 2006-06-01 WO disclosed