SCHEMBL69425

SCHEMBL69425

Oc1ccc(Br)c(Br)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
CA6 P23280 3/20 0.43
CA4 P22748 2/20 0.43
ALOX15 P16050 5/20 0.42
ALOX12 P18054 2/20 0.41
PTPN1 P18031 3/20 0.39
ALDH1A1 P00352 3/20 0.38
HPGD P15428 3/20 0.38
RECQL P46063 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
HSD17B10 Q99714 2/20 0.38
PIM1 P11309 1/20 0.38
ADAMTS4 O75173 1/20 0.38
EGFR P00533 1/20 0.38
LMNA P02545 1/20 0.38
FYN P06241 1/20 0.38
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL581815 0.81 CA1 (0.48) CA1CA2CA6CA4ALOX15
SCHEMBL37621 0.79 ALOX15 (0.43) CA1CA2CA6CA4ALOX15
SCHEMBL25414587 0.79 ALOX15 (0.43) CA1CA2CA6CA4ALOX15
SCHEMBL94834 0.79 ALOX15 (0.43) CA1CA2CA6CA4ALOX15
SCHEMBL7155617 0.78 PTPN1 (0.46) ALOX15ALOX12PTPN1ALDH1A1TSHR
SCHEMBL31147172 0.77 ALOX15 (0.42) CA1CA2CA6CA4ALOX15
SCHEMBL28786223 0.77 ALOX15 (0.42) CA1CA2CA6CA4ALOX15
SCHEMBL10727450 0.77 ALOX15 (0.42) CA1CA2CA6CA4ALOX15
SCHEMBL5803280 0.77 ALOX15 (0.42) CA1CA2CA6CA4ALOX15
Bromide SCHEMBL11723996 0.77 ALOX15 (0.42) CA1CA2CA6CA4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023056960-A1 SINGLE MOLECULE IDENTIFICATION WITH A REACTIVE HETERO-NANOPORE NANJING UNIVERSITY (CN) 2023-04-13 WO claimed
CN-100358933-C Fluorescent sensing materials made of conjugated polymer and process for preparing same UNIV FUDAN (CN) 2008-01-02 CN claimed
CN-1827664-A Fluorescent sensing materials made of conjugated polymer and process for preparing same UNIV FUDAN (CN) 2006-09-06 CN claimed
WO-2023056960-A1 SINGLE MOLECULE IDENTIFICATION WITH A REACTIVE HETERO-NANOPORE NANJING UNIVERSITY (CN) 2023-04-13 WO disclosed
CN-111171085-B Rhamnose donor protected by orthocarbonate, and preparation method and application thereof 山东大学 2022-12-06 CN disclosed
CN-112898827-B Ultraviolet curing packaging ink based on silicon-oxygen side chain-containing two-dimensional acrylate monomer and use method and application thereof 西安思摩威新材料有限公司 2022-10-18 CN disclosed
CN-113773699-A Ultraviolet curing packaging ink based on two-dimensional epoxy monomer containing silicon-oxygen side chain, use method and application thereof 西安思摩威新材料有限公司 2021-12-10 CN disclosed
CN-112898827-A Ultraviolet curing packaging ink based on silicon-oxygen side chain-containing two-dimensional acrylate monomer and use method and application thereof 西安思摩威新材料有限公司 2021-06-04 CN disclosed
US-9981887-B1 Synthesis of phenylethynylbenzenes THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2018-05-29 US disclosed
US-9981887-B1 Synthesis of phenylethynylbenzenes THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2018-05-29 US disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
CN-101473386-A Method for producing conductive material MITSUBISHI PAPER MILLS LTD (JP) 2009-07-01 CN disclosed
CN-100358933-C Fluorescent sensing materials made of conjugated polymer and process for preparing same UNIV FUDAN (CN) 2008-01-02 CN disclosed
CN-1307232-C Conjugated polymers containing 2, 7-fluorenyl units and having improved properties CELANESE AG (DE) 2007-03-28 CN disclosed
CN-1827664-A Fluorescent sensing materials made of conjugated polymer and process for preparing same UNIV FUDAN (CN) 2006-09-06 CN disclosed
US-20030134824-A1 Beta-cyclodextrin dimers and phthalocyanines and uses thereof NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2003-07-17 US disclosed
WO-2003052060-A2 BETA-CYCLODEXTRIN DIMERS AND PHTHALOCYANINES AND USES THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2003-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 CA1 550/4885CA2 612/4885CA6 675/4885
US-20030134824-A1 Beta-cyclodextrin dimers and phthalocyanines and uses thereof CRY2, CRY1, HCCS CA1 975/4885CA2 94/4885CA6 648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.