Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 4/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523628 | 0.86 | PLA2G2C (0.39) | PLA2G2CSIRT6SIRT1FAAHTP53 | |
| SCHEMBL10417269 | 0.84 | CTSK (0.40) | PLA2G2CFAAHTP53MAPTCTSK | |
| SCHEMBL4612120 | 0.84 | GPR84 (0.44) | FAAHMAPTZDHHC20ZDHHC2GPR84 | |
| SCHEMBL16478000 | 0.83 | CTSK (0.54) | PLA2G2CSIRT6SIRT1PLA2G2ACTSK | |
| SCHEMBL6559575 | 0.81 | PLA2G2C (0.42) | PLA2G2CMAPTCTSKALDH1A1 | |
| SCHEMBL27041595 | 0.79 | CTSK (0.42) | PLA2G2CFAAHMAPK1CTSKCA1 | |
| SCHEMBL27041593 | 0.79 | CTSK (0.42) | PLA2G2CFAAHMAPK1CTSKCA1 | |
| SCHEMBL11296644 | 0.78 | — | — | |
| SCHEMBL24629598 | 0.77 | ALDH1A1 (0.35) | PLA2G2CCYP2D6MAPTCYP2C19ALDH1A1 | |
| SCHEMBL5971426 | 0.77 | CTSK (0.60) | PLA2G2CCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006087324-A2 | METHOD FOR PRODUCING AN N-(1-ARYL-ALK-1-ENYL)-ACETAMIDE OR N-(1-HETEROARYL-ALK-1-ENYL)-ACETAMIDE | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-24 | — | — | WO | claimed |
| WO-2006087324-A2 | METHOD FOR PRODUCING AN N-(1-ARYL-ALK-1-ENYL)-ACETAMIDE OR N-(1-HETEROARYL-ALK-1-ENYL)-ACETAMIDE | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-24 | — | — | WO | disclosed |