Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5818367 | 0.81 | PLA2G2C (0.46) | PLA2G2CALDH1A1MAPTCTSK | |
| SCHEMBL11523628 | 0.79 | PLA2G2C (0.39) | PLA2G2CALDH1A1MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL24629598 | 0.77 | ALDH1A1 (0.35) | PLA2G2CALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL22563673 | 0.76 | PLA2G2C (0.43) | PLA2G2CALDH1A1LMNAMAPTUSP2 | |
| SCHEMBL11296644 | 0.74 | — | — | |
| SCHEMBL6562004 | 0.73 | MAPT (0.46) | ALDH1A1LMNAMAPTUSP2SMN1; SMN2 | |
| Carbamic Acid SCHEMBL8213815 | 0.73 | MAPT (0.42) | PLA2G2CALDH1A1LMNAMAPTUSP2 | |
| Carbamic Acid SCHEMBL8216451 | 0.73 | MAPT (0.42) | PLA2G2CALDH1A1LMNAMAPTUSP2 | |
| SCHEMBL28354564 | 0.72 | KDM4E (0.33) | PLA2G2CALDH1A1MAPTSMN1; SMN2RECQL | |
| SCHEMBL3777018 | 0.70 | GNPAT (0.49) | PLA2G2CALDH1A1LMNAMAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990641-B1 | Process for the synthesis of alpha-substituted ring systems | BAYER CHEMICALS AG (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6235925-B1 | RING CLOSURE METHATHESIS AND NOBLE METAL CATALYSTS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | disclosed |
| EP-0990641-A1 | Process for the synthesis of alpha-substituted ring systems | Bayer Aktiengesellschaft (DE) | 2000-04-05 | — | — | EP | disclosed |