Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819315 | 1.00 | MEN1 (0.33) | MEN1KMT2AKDM4ECA12CA2 | |
| SCHEMBL11177653 | 0.77 | TSHR (0.42) | MEN1KMT2AKDM4E | |
| SCHEMBL8937844 | 0.74 | TSHR (0.40) | MEN1KMT2A | |
| SCHEMBL2215569 | 0.73 | CA4 (0.36) | MEN1KMT2AKDM4ECA12CA2 | |
| SCHEMBL1257089 | 0.71 | TSHR (0.43) | MEN1KMT2AKDM4E | |
| SCHEMBL5819699 | 0.71 | KDM4E (0.34) | KMT2AKDM4E | |
| SCHEMBL5819697 | 0.71 | KDM4E (0.34) | KMT2AKDM4E | |
| SCHEMBL7482314 | 0.70 | ALDH1A1 (0.33) | MEN1KMT2AKDM4ECA12CA2 | |
| SCHEMBL9288040 | 0.68 | TP53 (0.40) | — | |
| SCHEMBL9853509 | 0.68 | TSHR (0.50) | MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006138475-A2 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2006-12-28 | — | — | WO | claimed |
| WO-2006138475-A2 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2006-12-28 | — | — | WO | disclosed |