Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11177653 | 0.77 | TSHR (0.42) | TSHRALDH1A1MEN1KMT2AMTNR1A | |
| SCHEMBL2480675 | 0.76 | TSHR (0.44) | TSHRL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL6543119 | 0.75 | L3MBTL1 (0.42) | TSHRL3MBTL1ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2477834 | 0.75 | TSHR (0.42) | TSHRL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL5819315 | 0.74 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL5819307 | 0.74 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL2215569 | 0.73 | CA4 (0.36) | TSHRALDH1A1MEN1KMT2AMTNR1A | |
| SCHEMBL8704299 | 0.72 | MTNR1A (0.43) | TSHRL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL1257089 | 0.71 | TSHR (0.43) | TSHRL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL7626883 | 0.71 | KDM4E (0.42) | TSHRL3MBTL1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716085-A1 | Amino acid derivatives of paclitaxel | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-06-12 | — | — | EP | disclosed |
| US-5489589-A | ADMINSTERING AS ANTITUMOR AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-06 | — | — | US | disclosed |