Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.83 |
| ▸ | MEN1 | O00255 | 4/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | MAPT | P10636 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | NPC1 | O15118 | 1/20 | 0.76 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.62 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | COMT | P21964 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29813583 | 0.84 | EGFR (0.73) | EGFRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL16160385 | 0.84 | ALDH1A1 (0.68) | EGFRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL16160370 | 0.83 | FTO (0.76) | EGFRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29813596 | 0.83 | EGFR (0.72) | EGFRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14573318 | 0.83 | MEN1 (0.77) | EGFRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1405285 | 0.83 | MEN1 (0.77) | EGFRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1405287 | 0.83 | MEN1 (0.77) | EGFRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14185425 | 0.81 | EGFR (0.69) | EGFRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6375844 | 0.81 | EGFR (0.64) | EGFRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6375848 | 0.81 | EGFR (0.64) | EGFRMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006064296-A1 | PROCESS FOR THE PREPARATION OF (E)-N,N-DIETHYL-2-CYANO-3(3,4-DIHYDROXY-5-NITRO-PHENYL)-ACRYLAMIDE IN STABLE POLYMORPHIC FORM AND INTERMEDIATES OF THE PROCESS | ALKALOIDA KUTATO ES FEJLESZTÖ KFT (HU) | 2006-06-22 | — | — | WO | disclosed |