Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4921368 | 0.84 | ALDH1A1 (0.75) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL3042630 | 0.83 | ALDH1A1 (1.00) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL29744710 | 0.83 | ALDH1A1 (1.00) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL85672 | 0.83 | ALDH1A1 (0.73) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL30928952 | 0.83 | ALDH1A1 (0.73) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL1127011 | 0.83 | ALDH1A1 (0.73) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL14464189 | 0.81 | ALDH1A1 (0.79) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL5697459 | 0.79 | ALDH1A1 (0.68) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL18396735 | 0.78 | ALDH1A1 (0.66) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL78723 | 0.78 | ALDH1A1 (0.62) | ALDH1A1KMT2ALMNAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006135383-A2 | INDAZOLES | MYRIAD GENETICS, INC. (US) | 2006-12-21 | — | — | WO | disclosed |