SCHEMBL5820601

SCHEMBL5820601

CC=C(CCN=C=O)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.36
HDAC2 Q92769 2/20 0.36
HDAC3 O15379 1/20 0.36
NCOR2 Q9Y618 1/20 0.36
MTNR1A P48039 2/20 0.34
MTNR1B P49286 2/20 0.34
AKT1 P31749 2/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
PDPK1 O15530 2/20 0.33
KMT2A Q03164 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28491311 0.78 L3MBTL1 (0.36) HDAC1HDAC2HDAC3CES2CES1
SCHEMBL5818645 0.75 MAOA (0.40) CYP1A2
SCHEMBL9003708 0.72 NR4A2 (0.57) HDAC1HDAC2HDAC3NCOR2MTNR1A
SCHEMBL9003706 0.72 NR4A2 (0.57) HDAC1HDAC2HDAC3NCOR2MTNR1A
SCHEMBL28039877 0.71 L3MBTL1 (0.38) HDAC1HDAC2HDAC3CES2CES1
SCHEMBL7803886 0.71 CES2 (0.50) HDAC1HDAC2HDAC3NCOR2CES2
SCHEMBL6438248 0.71 HDAC1 (0.44) HDAC1HDAC2HDAC3NCOR2MTNR1A
SCHEMBL7803887 0.71 CES2 (0.50) HDAC1HDAC2HDAC3NCOR2CES2
SCHEMBL6438252 0.71 HDAC1 (0.44) HDAC1HDAC2HDAC3NCOR2MTNR1A
SCHEMBL6438249 0.71 HDAC1 (0.44) HDAC1HDAC2HDAC3NCOR2MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006068852-A1 SOLVENT RESISTANT IMAGEABLE ELEMENT EASTMAN KODAK COMPANY (US) 2006-06-29 WO disclosed
US-6969579-B1 top layer containing a co-polymer of an unsaturated compound containing an imide group and a comonomer selected from an acryl imides, acrylonitriles, acryalmides and acrylic acids; chemical resistance printing plate EASTMAN KODAK COMPANY (US) 2005-11-29 US disclosed