Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820709 | 0.81 | MAPT (0.47) | MAPK9MAPK8MAPK10MAPK14MAPK13 | |
| SCHEMBL5814608 | 0.78 | MAPK9 (0.43) | MAPK9MAPK8MAPK10MAPK14MAPK13 | |
| SCHEMBL5806904 | 0.78 | MAPK9 (0.43) | MAPK9MAPK8MAPK10MAPK14MAPK13 | |
| SCHEMBL5814956 | 0.76 | MAPK9 (0.42) | MAPK9MAPK8MAPK10MAPK14MAPK13 | |
| SCHEMBL5805633 | 0.74 | MAPT (0.53) | MAPK9MAPK8MAPK10MAPK14MAPK13 | |
| SCHEMBL5805306 | 0.70 | DRD2 (0.44) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL4961478 | 0.68 | MAPK14 (0.45) | MAPK14MAPK13MAPK12MAPK11RIPK3 | |
| Hydrochloric Acid SCHEMBL749696 | 0.68 | MAPK14 (0.44) | MAPK14MAPK13MAPK12MAPK11RIPK3 | |
| SCHEMBL5819589 | 0.66 | SRC (0.53) | MAPK14ALDH1A1 | |
| SCHEMBL5804303 | 0.66 | SRC (0.52) | MAPK14MAPK13MAPK12MAPK11CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117657-A1 | TRIAZOLONE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2006-11-09 | — | — | WO | disclosed |