Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 3/20 | 0.40 |
| ▸ | FABP4 | P15090 | 3/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | RPA1 | P27694 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4163228 | 0.92 | PTGS2 (0.40) | KDM4EMAPTPIM1GFERTDP1 | |
| SCHEMBL28818910 | 0.88 | KDM4E (0.39) | KDM4EMAPTPIM1GFERTDP1 | |
| SCHEMBL5805083 | 0.83 | EGFR (0.47) | MAPTTDP1SMN1; SMN2CHEK1EGFR | |
| SCHEMBL5808870 | 0.81 | PTGS2 (0.39) | LMNAPTGS2 | |
| SCHEMBL4471440 | 0.80 | ALDH1A1 (0.55) | KDM4EMAPTPIM1GFERTDP1 | |
| SCHEMBL5821884 | 0.80 | RAB9A (0.45) | KDM4EMAPTTDP1SMN1; SMN2LMNA | |
| SCHEMBL5804954 | 0.79 | GCGR (0.49) | MAPTSMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL5809257 | 0.78 | TP53 (0.47) | SMN1; SMN2KDRLMNAALDH1A1HPGD | |
| SCHEMBL5805311 | 0.77 | HTT (0.45) | MAPTSMN1; SMN2CHEK1EGFRKDR | |
| SCHEMBL4169210 | 0.77 | HMGCR (0.47) | KDM4EMAPTSMN1; SMN2CHEK1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006110918-A1 | PYRROLE COMPOUNDS AND USES THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2006-10-19 | — | — | WO | disclosed |