Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.50 |
| ▸ | HTR1A | P08908 | 7/20 | 0.47 |
| ▸ | HTR7 | P34969 | 4/20 | 0.47 |
| ▸ | FPR2 | P25090 | 3/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.46 |
| ▸ | DRD2 | P14416 | 6/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.46 |
| ▸ | HTR2A | P28223 | 6/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.46 |
| ▸ | HRH1 | P35367 | 6/20 | 0.46 |
| ▸ | DRD3 | P35462 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5809446 | 0.99 | KDM1A (0.49) | KDM1AHTR1AHTR7FPR2ADRA2A | |
| SCHEMBL5807697 | 0.91 | KDM1A (0.57) | KDM1AHTR1AHTR7ADRA2ADRD2 | |
| Hydrochloric Acid SCHEMBL5808304 | 0.90 | KDM1A (0.56) | KDM1AHTR1AHTR7ADRA2ADRD2 | |
| SCHEMBL5235676 | 0.83 | ADRA1D (0.45) | HTR1AHTR7SLC6A2SLC6A4LMNA | |
| SCHEMBL5805711 | 0.82 | KDM1A (0.55) | KDM1AHTR1AFPR2ADRA2ADRD2 | |
| Hydrochloric Acid SCHEMBL5807341 | 0.82 | KDM1A (0.54) | KDM1AHTR1AFPR2ADRA2ADRD2 | |
| SCHEMBL4538417 | 0.81 | ADRA1B (0.48) | HTR1AHTR7DRD2ADRA1AKCNH2 | |
| SCHEMBL5422270 | 0.81 | HTR1A (0.49) | HTR1AHTR7ADRA2ADRD2SLC6A2 | |
| SCHEMBL5821135 | 0.81 | KDM1A (0.46) | KDM1AHTR1AHTR7ADRA2ADRD2 | |
| Hydrochloric Acid SCHEMBL5416920 | 0.80 | HTR1A (0.49) | HTR1AHTR7ADRA2ADRD2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117760-A1 | ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |