Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | ITK | Q08881 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791288 | 0.83 | MAPK14 (0.43) | TDP1CTSK | |
| Trifluoroacetic Acid SCHEMBL5794976 | 0.83 | ALDH1A1 (0.43) | MEN1KMT2AACACB | |
| Trifluoroacetic Acid SCHEMBL5794574 | 0.81 | CTSK (0.48) | CTSK | |
| Trifluoroacetic Acid SCHEMBL5791067 | 0.81 | CTSL (0.41) | TRPV1ITKTLR7CTSKTRPM8 | |
| Trifluoroacetic Acid SCHEMBL5793434 | 0.78 | CTSK (0.44) | MEN1KMT2ACTSK | |
| Trifluoroacetic Acid SCHEMBL5791892 | 0.75 | CTSK (0.38) | CTSK | |
| Trifluoroacetic Acid SCHEMBL5792613 | 0.75 | TSHR (0.39) | MEN1KMT2ATDP1CTSK | |
| Trifluoroacetic Acid SCHEMBL5808826 | 0.75 | CTSK (0.37) | CTSK | |
| Trifluoroacetic Acid SCHEMBL5791291 | 0.73 | CTSK (0.38) | MEN1KMT2ACTSK | |
| Trifluoroacetic Acid SCHEMBL5794182 | 0.73 | CTSL (0.41) | MEN1KMT2ACTSKEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027211-A1 | 2,4-SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | claimed |