Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | TBK1 | Q9UHD2 | 8/20 | 0.43 |
| ▸ | IKBKE | Q14164 | 6/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | GPR4 | P46093 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5790648 | 0.89 | CTSK (0.44) | CTSKCTSLCTSSCTSBTBK1 | |
| Trifluoroacetic Acid SCHEMBL5793410 | 0.83 | CTSK (0.65) | CTSKCTSLCTSSCTSBTBK1 | |
| Trifluoroacetic Acid SCHEMBL5794976 | 0.81 | ALDH1A1 (0.43) | HRH3 | |
| Trifluoroacetic Acid SCHEMBL5821153 | 0.81 | MEN1 (0.36) | CTSK | |
| Trifluoroacetic Acid SCHEMBL5592645 | 0.80 | CTSS (0.47) | CTSKCTSLCTSSCTSBTBK1 | |
| Trifluoroacetic Acid SCHEMBL5592759 | 0.80 | CTSL (0.47) | CTSKCTSLCTSSCTSBTBK1 | |
| Trifluoroacetic Acid SCHEMBL5592942 | 0.80 | CTSS (0.47) | CTSKCTSLCTSSCTSBTBK1 | |
| Trifluoroacetic Acid SCHEMBL5592864 | 0.80 | CTSS (0.47) | CTSKCTSLCTSSCTSBTBK1 | |
| Trifluoroacetic Acid SCHEMBL5804566 | 0.79 | CTSK (0.46) | CTSKCTSLCTSSCTSBTBK1 | |
| Trifluoroacetic Acid SCHEMBL3317688 | 0.79 | CTSK (0.54) | CTSKCTSLCTSSCTSBTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027211-A1 | 2,4-SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | claimed |