SCHEMBL5821162

SCHEMBL5821162

CCCCCc1cc(C(C)(C)C)cc2c1-c1ccc(C(C)(C)C)cc1C2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 1/20 0.36
CNR1 P21554 6/20 0.33
CNR2 P34972 6/20 0.33
TRPV1 Q8NER1 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
ELANE P08246 1/20 0.31
CD69 Q07108 1/20 0.31
MEN1 O00255 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALOX5 P09917 1/20 0.31
MAPT P10636 1/20 0.31
TYR P14679 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9761249 0.80 PON1 (0.38) CYP1A2CYP2C19ELANECD69MAPT
SCHEMBL5819033 0.77 HRH3 (0.34) CYP1A2CYP2C19ELANECD69CYP2D6
SCHEMBL16442396 0.75 METAP1 (0.36) ELANEMEN1TP53CYP3A4ALOX5
SCHEMBL5437344 0.75 ALDH1A1 (0.37) CYP1A2CYP2C19ELANECD69MEN1
SCHEMBL3888554 0.72 ALDH1A1 (0.35) CYP1A2CYP2C19ELANECD69MEN1
SCHEMBL25633605 0.72 ELANE (0.36) CYP1A2CYP2C19ELANECD69MEN1
SCHEMBL5820431 0.72 ALDH1A1 (0.35) CYP1A2CYP2C19ELANECD69MEN1
SCHEMBL30430052 0.72 ALDH1A1 (0.35) CYP1A2CYP2C19ELANECD69MEN1
SCHEMBL8857107 0.72 PNMT (0.39) GHSRCNR1CNR2CYP1A2CYP2C19
SCHEMBL40372 0.72 ALDH1A1 (0.45) CYP1A2CYP2C19ELANECD69MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006137818-A1 CATALYST COMPONENTS AND THEIR USE IN THE POLYMERIZATION OF OLEFINS FINA TECHNOLOGY, INC. (US) 2006-12-28 WO disclosed
US-20050148460-A1 Catalyst components and their use in the polymerization of olefins FINA TECHNOLOGY, INC. 2005-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050148460-A1 Catalyst components and their use in the polymerization of olefins NPY5R, SSTR5, FGR GHSR 1310/4885CNR1 875/4885CNR2 879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.