Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 2/20 | 0.58 |
| ▸ | TDP2 | O95551 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9178962 | 0.82 | APAF1 (0.60) | APAF1TDP2SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL25649144 | 0.80 | APAF1 (0.58) | APAF1TDP2SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL11799339 | 0.80 | APAF1 (0.58) | APAF1TDP2SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL30304915 | 0.75 | APAF1 (0.62) | APAF1TDP2SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL29678361 | 0.75 | APAF1 (1.00) | APAF1TDP2SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL461648 | 0.75 | APAF1 (1.00) | APAF1TDP2SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL28758923 | 0.73 | APAF1 (0.60) | APAF1TDP2SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL16453655 | 0.73 | APAF1 (0.60) | APAF1TDP2SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL29834814 | 0.73 | APAF1 (0.60) | APAF1TDP2SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL11801950 | 0.72 | APAF1 (0.52) | APAF1TDP2SMN1; SMN2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006107827-A1 | SKIN BONDING PROCESS | CREIGHTON UNIVERSITY (US) | 2006-10-12 | — | — | WO | disclosed |