SCHEMBL16453655

SCHEMBL16453655

NC(=O)C1=C(O)C(=O)c2ccccc2C1=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APAF1 O14727 2/20 0.60
TDP2 O95551 2/20 0.60
FGFR1 P11362 6/20 0.59
FGFR2 P21802 6/20 0.59
FGFR4 P22455 6/20 0.59
FGFR3 P22607 6/20 0.59
SRC P12931 3/20 0.59
CRHBP P24387 1/20 0.59
CRHR2 Q13324 1/20 0.59
KEAP1 Q14145 1/20 0.47
NFE2L2 Q16236 1/20 0.47
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
CDC25B P30305 1/20 0.44
P2RX7 Q99572 3/20 0.44
MAPT P10636 3/20 0.43
MAOA P21397 2/20 0.43
MCL1 Q07820 2/20 0.43
BCL2 P10415 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1210571 0.92 FGFR1 (0.59) APAF1TDP2FGFR1FGFR2FGFR4
SCHEMBL5491718 0.87 FGFR1 (0.68) APAF1TDP2FGFR1FGFR2FGFR4
SCHEMBL30304915 0.81 APAF1 (0.62) APAF1TDP2FGFR1FGFR2FGFR4
SCHEMBL29834814 0.79 APAF1 (0.60) APAF1TDP2FGFR1FGFR2FGFR4
SCHEMBL9178962 0.79 APAF1 (0.60) APAF1TDP2FGFR1FGFR2FGFR4
SCHEMBL28758923 0.79 APAF1 (0.60) APAF1TDP2FGFR1FGFR2FGFR4
SCHEMBL29678361 0.77 APAF1 (1.00) APAF1TDP2MEN1KMT2ACDC25B
SCHEMBL461648 0.77 APAF1 (1.00) APAF1TDP2MEN1KMT2ACDC25B
SCHEMBL144665 0.75 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL11799339 0.73 APAF1 (0.58) APAF1TDP2MEN1KMT2ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113066992-B Alkaline aqueous single flow battery based on double-metal MOF positive electrode and organic matter negative electrode 常州大学 2022-06-17 CN claimed
CN-113066992-A Alkaline aqueous single flow battery based on double-metal MOF positive electrode and organic matter negative electrode 常州大学 2021-07-02 CN claimed
CN-113066992-B Alkaline aqueous single flow battery based on double-metal MOF positive electrode and organic matter negative electrode 常州大学 2022-06-17 CN disclosed
CN-113066992-A Alkaline aqueous single flow battery based on double-metal MOF positive electrode and organic matter negative electrode 常州大学 2021-07-02 CN disclosed
EP-3041586-B1 SKIN CARE COMPOSITION UNILEVER NV (NL) 2016-11-30 EP disclosed
US-20160166628-A1 SKIN CARE COMPOSITION CONOPCO, INC., D/B/A UNILEVER (US) 2016-06-16 US disclosed
US-20160166628-A1 SKIN CARE COMPOSITION CONOPCO, INC., D/B/A UNILEVER (US) 2016-06-16 US disclosed
WO-2015018631-A1 SKIN CARE COMPOSITION UNILEVER N.V. (NL) 2015-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160166628-A1 SKIN CARE COMPOSITION CUTA, RBP4, RBP1 APAF1 3205/4885TDP2 737/4885FGFR1 4325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.