Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 2/20 | 0.60 |
| ▸ | TDP2 | O95551 | 2/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | MPI | P34949 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821846 | 0.82 | APAF1 (0.58) | APAF1TDP2HSP90AA1HSP90AB1RAB9A | |
| SCHEMBL11799339 | 0.82 | APAF1 (0.58) | APAF1TDP2HSP90AA1HSP90AB1RAB9A | |
| SCHEMBL25649144 | 0.82 | APAF1 (0.58) | APAF1TDP2HSP90AA1HSP90AB1RAB9A | |
| SCHEMBL30304915 | 0.81 | APAF1 (0.62) | APAF1TDP2HSP90AA1HSP90AB1RAB9A | |
| SCHEMBL28758923 | 0.79 | APAF1 (0.60) | APAF1TDP2HSP90AA1HSP90AB1RAB9A | |
| SCHEMBL27460293 | 0.79 | HSP90AA1 (0.59) | APAF1HSP90AA1HSP90AB1RAB9AMAPT | |
| SCHEMBL30583758 | 0.79 | HSP90AA1 (0.59) | APAF1HSP90AA1HSP90AB1RAB9AMAPT | |
| SCHEMBL16453655 | 0.79 | APAF1 (0.60) | APAF1TDP2HSP90AA1HSP90AB1RAB9A | |
| SCHEMBL29834814 | 0.79 | APAF1 (0.60) | APAF1TDP2HSP90AA1HSP90AB1RAB9A | |
| SCHEMBL461648 | 0.77 | APAF1 (1.00) | APAF1TDP2RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498707-B1 | Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent | OREAL (FR) | 1995-08-02 | — | — | EP | claimed |
| EP-0498707-A1 | Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent | L'OREAL (FR) | 1992-08-12 | — | — | EP | claimed |
| CN-101687752-B | Process for the preparation oftrans-2,3-disubstituted naphthoquinones | LABORATORIO CHIMICO INT SPA | 2013-01-30 | — | — | CN | disclosed |
| CN-101687752-A | Process for the preparation oftrans-2,3-disubstituted naphthoquinones | LABORATORIO CHIMICO INT SPA | 2010-03-31 | — | — | CN | disclosed |
| EP-0498707-B1 | Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent | OREAL (FR) | 1995-08-02 | — | — | EP | disclosed |
| US-5275626-A | Hair dyes | L'OREAL (FR) | 1994-01-04 | — | — | US | disclosed |
| EP-0498707-A1 | Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent | L'OREAL (FR) | 1992-08-12 | — | — | EP | disclosed |