Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.76 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.49 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.49 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.49 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12827331 | 0.87 | TOP1 (1.00) | TOP1POLMPOLKPOLLPOLH | |
| SCHEMBL9006495 | 0.80 | TOP1 (0.67) | TOP1POLMPOLKPOLLPOLH | |
| SCHEMBL29617334 | 0.76 | KMT2A (0.55) | KMT2AMAPTHSD17B10CYP3A4MEN1 | |
| SCHEMBL1287104 | 0.75 | TOP1 (0.65) | TOP1POLMPOLKPOLLPOLH | |
| SCHEMBL2879378 | 0.75 | ESR1 (0.60) | KMT2AMAPTHSD17B10CYP3A4MEN1 | |
| SCHEMBL9006775 | 0.74 | TOP1 (0.58) | TOP1POLMPOLKPOLLPOLH | |
| SCHEMBL17744861 | 0.73 | TOP1 (0.54) | TOP1KMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL10394363 | 0.72 | POLM (0.63) | TOP1POLMPOLKPOLLPOLH | |
| SCHEMBL3054875 | 0.72 | POLM (0.63) | TOP1POLMPOLKPOLLPOLH | |
| SCHEMBL6662940 | 0.72 | TOP1 (0.60) | TOP1POLMPOLKPOLLPOLH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006107827-A1 | SKIN BONDING PROCESS | CREIGHTON UNIVERSITY (US) | 2006-10-12 | — | — | WO | disclosed |