Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191589 | 1.00 | APP (0.35) | APPLMNAL3MBTL1TDP1MAPK1 | |
| SCHEMBL8593832 | 0.88 | LMNA (0.34) | LMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL1377219 | 0.86 | LMNA (0.35) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL5822045 | 0.86 | LMNA (0.35) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL3512233 | 0.86 | LMNA (0.35) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL9189452 | 0.84 | APP (0.35) | APPLMNAL3MBTL1TDP1MAPK1 | |
| SCHEMBL707743 | 0.81 | MEN1 (0.42) | LMNATDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL8603750 | 0.81 | MEN1 (0.42) | LMNATDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL9634744 | 0.81 | MEN1 (0.42) | LMNATDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL1582160 | 0.81 | MEN1 (0.42) | LMNATDP1ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218112-B1 | SCREENING PEPTIDES FOR ABILITY TO TRANSFECT CELLS WITH NUCLEIC ACID BY DETECTING CHANGE IN SURFACE PLASMON RESONANCE CAUSED BY BINDING/DISSOCIATION OF PEPTIDE TO NUCLEIC ACID IMMOBILIZED ON SENSOR CHIP, CALCULATING EQUILIBRIUM CONSTANT | COBRA THERAPEUTICS LIMITED (GB) | 2001-04-17 | — | — | US | disclosed |
| WO-1989004672-A1 | DERIVATIVES OF LINCOSAMINIDE ANTIBIOTICS | THE UPJOHN COMPANY (US) | 1989-06-01 | — | — | WO | disclosed |