Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | BCL9 | O00512 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL707743 | 1.00 | MEN1 (0.42) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1582160 | 1.00 | MEN1 (0.42) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8603750 | 1.00 | MEN1 (0.42) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10583549 | 0.99 | MEN1 (0.41) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10582879 | 0.96 | KMT2A (0.43) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7913872 | 0.81 | APP (0.35) | CYP3A4LMNATDP1ALDH1A1TSHR | |
| SCHEMBL9191589 | 0.81 | APP (0.35) | CYP3A4LMNATDP1ALDH1A1TSHR | |
| SCHEMBL8593832 | 0.81 | LMNA (0.34) | MEN1KMT2AGAALMNATDP1 | |
| SCHEMBL2786997 | 0.81 | KMT2A (0.40) | MEN1KMT2AGAABCL9CTNNB1 | |
| SCHEMBL5822045 | 0.80 | LMNA (0.35) | LMNATDP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272691-B1 | ENZYME IMMUNOASSAY | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1992-07-08 | — | — | EP | disclosed |
| EP-0272691-A2 | Enzyme immunoassay | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1988-06-29 | — | — | EP | disclosed |