SCHEMBL707743

SCHEMBL707743

O=C[C@H](Oc1ccc([N+](=O)[O-])cc1)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
ALOX12 P18054 1/20 0.42
ATM Q13315 1/20 0.42
GAA P10253 2/20 0.40
BCL9 O00512 1/20 0.40
CTNNB1 P35222 1/20 0.40
LMNA P02545 1/20 0.39
HTR2A P28223 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
MAPT P10636 2/20 0.38
NPC1 O15118 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1582160 1.00 MEN1 (0.42) MEN1KMT2ACYP1A2CYP3A4CYP2C9
SCHEMBL9634744 1.00 MEN1 (0.42) MEN1KMT2ACYP1A2CYP3A4CYP2C9
SCHEMBL8603750 1.00 MEN1 (0.42) MEN1KMT2ACYP1A2CYP3A4CYP2C9
SCHEMBL10583549 0.99 MEN1 (0.41) MEN1KMT2ACYP1A2CYP3A4CYP2C9
SCHEMBL10582879 0.96 KMT2A (0.43) MEN1KMT2ACYP1A2CYP3A4CYP2C9
SCHEMBL7913872 0.81 APP (0.35) CYP3A4LMNATDP1ALDH1A1TSHR
SCHEMBL9191589 0.81 APP (0.35) CYP3A4LMNATDP1ALDH1A1TSHR
SCHEMBL8593832 0.81 LMNA (0.34) MEN1KMT2AGAALMNATDP1
SCHEMBL2786997 0.81 KMT2A (0.40) MEN1KMT2AGAABCL9CTNNB1
SCHEMBL5822045 0.80 LMNA (0.35) LMNATDP1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3551194-B1 GLYCAN POLYMERS AND RELATED METHODS THEREOF DSM NUTRITIONAL PRODUCTS LLC (US) 2023-10-18 EP disclosed
US-20200390798-A1 GLYCAN POLYMERS AND RELATED METHODS THEREOF HERCULES CAPITAL, INC. 2020-12-17 US disclosed
CN-105969675-B A kind of low carbohydrase Producing Strain gene knockout recombinant bacterium for turning glycosides enzyme background and its building and application 华南理工大学 2019-11-15 CN disclosed
CN-110441410-A The chromatography detection method of compound in hippophae rhamnoides NORTHWEST INST PLATEAU BIO CAS 2019-11-12 CN disclosed
CN-110407906-A The method of triterpenoid is separated and prepared from hippophae rhamnoides NORTHWEST INST PLATEAU BIO CAS 2019-11-05 CN disclosed
CN-110368391-A Triterpenoid is preparing the purposes in hypoglycemic Related product 中国科学院西北高原生物研究所 2019-10-25 CN disclosed
US-20190290675-A1 GLYCAN POLYMERS AND RELATED METHODS THEREOF HERCULES CAPITAL, INC. 2019-09-26 US disclosed
CN-110025604-A Purposes of the hypericin in the Related product that preparation inhibits glucosidase activity 中国科学院西北高原生物研究所 2019-07-19 CN disclosed
CN-109336887-A A kind of benzimidazole and chiral heterocycle class compound and its preparation method and application 中山大学 2019-02-15 CN disclosed
CN-109010456-A A method of extracting alpha-glucosidase restrainer from raspberry 江西师范大学 2018-12-18 CN disclosed
WO-2000047174-A1 COMPOSITIONS FOR CONTROLLING BACTERIAL COLONIZATION PHARMACAL BIOTECHNOLOGIES, LLC (US) 2000-08-17 WO disclosed
WO-2000047175-A1 ORAL COMPOSITIONS AND METHODS OF PRODUCTION THEREOF PHARMACAL BIOTECHNOLOGIES, LLC (US) 2000-08-17 WO disclosed
EP-1023084-A1 COMPOSITIONS FOR CONTROLLING BACTERIAL COLONIZATION Pharmacal Biotechnologies, Inc. (US) 2000-08-02 EP disclosed
WO-1999018999-A1 COMPOSITIONS FOR CONTROLLING BACTERIAL COLONIZATION PHARMACAL BIOTECHNOLOGIES, INC. (US) 1999-04-22 WO disclosed
US-5871714-A Compositions for controlling bacterial colonization PHARMACAL BIOTECHNOLOGIES, INC. (US) 1999-02-16 US disclosed
US-5859333-A INCORPORATING INTO GENOME OF PLANT A DONOR GENE ENCODING A STARCH PRIMER FOR ALTERED ABILITY TO SYNTHESIZE STARCH ZENECA LIMITED (GB) 1999-01-12 US disclosed
US-5540834-A PYROLYSIS, SINTERING REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1996-07-30 US disclosed
US-5486458-A ANALYZING BLOOD AND CONVERSION OF MALTOSE INTO GLUCOSE USING GLUCOSIDASE DERIVED FROM BACILLUS, PHOSPHORYLATION TO SEPARATE GLUCOSE AND SUGARS NITTO BOSEKI CO., LTD. (JP) 1996-01-23 US disclosed
EP-0658208-A1 NOVEL PLANTS AND PROCESSES FOR OBTAINING THEM ZENECA LIMITED (GB) 1995-06-21 EP disclosed
WO-1994004693-A2 NOVEL PLANTS AND PROCESSES FOR OBTAINING THEM ZENECA LIMITED (GB) 1994-03-03 WO disclosed