Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4292449 | 0.76 | KDM4E (0.48) | KDM4EHSD17B10HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL20893365 | 0.72 | RAB9A (0.57) | KDM4EHSD17B10HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL9670397 | 0.68 | KDM4E (0.57) | KDM4EHSD17B10HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL24187368 | 0.67 | KDM4E (0.56) | KDM4EHSD17B10HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4297543 | 0.67 | KDM4E (0.56) | KDM4EHSD17B10HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL1586265 | 0.67 | SMN1; SMN2 (0.50) | KDM4EHSD17B10HPGDSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28961226 | 0.66 | KDM4E (0.55) | KDM4EHSD17B10HPGDSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30396830 | 0.66 | KDM4E (0.55) | KDM4EHSD17B10HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL1585673 | 0.66 | KDM4E (0.42) | KDM4EHSD17B10HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL7970314 | 0.65 | ALDH1A1 (0.58) | KDM4EHSD17B10SMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006121904-A1 | GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE (GIP) RECEPTOR AGONISTS AND THEIR PHARMACOLOGICAL METHODS OF USE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-11-16 | — | — | WO | disclosed |