Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17035245 | 0.86 | BCHE (0.71) | BCHEPTGS2SMN1; SMN2KMT2AALOX15 | |
| SCHEMBL5039203 | 0.85 | BCHE (0.64) | BCHEPTGS2PKMSMN1; SMN2KMT2A | |
| SCHEMBL6261634 | 0.82 | BCHE (0.70) | BCHEPTGS2SMN1; SMN2KMT2AGAA | |
| SCHEMBL17034707 | 0.82 | BCHE (0.65) | BCHEPTGS2SMN1; SMN2KMT2AGAA | |
| Ampyrone SCHEMBL11674586 | 0.82 | BCHE (1.00) | BCHEPTGS2SMN1; SMN2KMT2AGAA | |
| Ampyrone SCHEMBL128544 | 0.82 | BCHE (1.00) | BCHEPTGS2SMN1; SMN2KMT2AGAA | |
| Ampyrone SCHEMBL18159502 | 0.82 | BCHE (1.00) | BCHEPTGS2SMN1; SMN2KMT2AGAA | |
| SCHEMBL396148 | 0.81 | BCHE (0.60) | BCHEPTGS2KMT2AMEN1ALOX15 | |
| Ampyrone SCHEMBL1830291 | 0.80 | BCHE (0.96) | BCHEPTGS2SMN1; SMN2KMT2AGAA | |
| Ampyrone SCHEMBL10746988 | 0.80 | BCHE (0.96) | BCHEPTGS2SMN1; SMN2KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826761-A | FOR COLORIMETRIC ANALYSIS | FUJI PHOTO FILM CO, LTD. (JP) | 1989-05-02 | — | — | US | claimed |
| US-4822891-A | ANALYZING HYDROGEN PEROXIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1989-04-18 | — | — | US | claimed |
| US-20170088546-A1 | CARBOXAMIDE INHIBITORS | NOVARTIS AG (CH) | 2017-03-30 | — | — | US | disclosed |
| US-20170088546-A1 | CARBOXAMIDE INHIBITORS | NOVARTIS AG (CH) | 2017-03-30 | — | — | US | disclosed |
| US-20170088546-A1 | CARBOXAMIDE INHIBITORS | NOVARTIS AG (CH) | 2017-03-30 | — | — | US | disclosed |
| WO-2006136493-A1 | ANTIPYRINE-INDANDIONE BASED AZO METAL COMPLEX DYES AND THEIR USE IN OPTICAL LAYERS FOR OPTICAL DATA RECORDING | CLARIANT FINANCE (BVI) LIMITED (US) | 2006-12-28 | — | — | WO | disclosed |
| US-4826761-A | FOR COLORIMETRIC ANALYSIS | FUJI PHOTO FILM CO, LTD. (JP) | 1989-05-02 | — | — | US | disclosed |
| US-4822891-A | ANALYZING HYDROGEN PEROXIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| US-4711963-A | 4-amino-2-methyl-3-phenyl-1-(2,4,6-trichlorophenyl)-3-pyrazolin-5-one | FUJI PHOTO FILM CO., LTD. (JP) | 1987-12-08 | — | — | US | disclosed |
| EP-0101945-A1 | Multilayer analytical element | FUJI PHOTO FILM CO., LTD. (JP) | 1984-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088546-A1 | CARBOXAMIDE INHIBITORS | SMURF1, SMURF2, SMYD2 | BCHE 4333/4885PTGS2 2129/4885PKM 3558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.