Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | SLC6A7 | Q99884 | 11/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3578419 | 0.84 | SLC6A7 (0.77) | KDM4ESLC6A7ALDH1A1L3MBTL1SLC6A3 | |
| SCHEMBL4789639 | 0.84 | SLC6A7 (0.68) | KDM4ESLC6A7ALDH1A1L3MBTL1SLC6A3 | |
| SCHEMBL5823601 | 0.83 | SLC6A7 (0.62) | KDM4ESLC6A7ALDH1A1L3MBTL1SLC6A3 | |
| SCHEMBL3580304 | 0.79 | SLC6A7 (0.70) | KDM4ESLC6A7ALDH1A1L3MBTL1SLC6A3 | |
| SCHEMBL3817716 | 0.75 | SLC6A7 (0.63) | KDM4ESLC6A7ALDH1A1L3MBTL1SLC6A3 | |
| SCHEMBL3628401 | 0.73 | SLC6A7 (0.70) | KDM4ESLC6A7ALDH1A1L3MBTL1SLC6A3 | |
| SCHEMBL3820146 | 0.73 | SLC6A7 (0.65) | KDM4ESLC6A7ALDH1A1L3MBTL1SLC6A3 | |
| SCHEMBL4695977 | 0.72 | SLC6A7 (0.62) | KDM4ESLC6A7ALDH1A1L3MBTL1DRD2 | |
| SCHEMBL14182187 | 0.72 | SLC6A7 (0.72) | KDM4ESLC6A7ALDH1A1L3MBTL1SLC6A3 | |
| SCHEMBL5935798 | 0.72 | SLC6A7 (0.59) | KDM4ESLC6A7ALDH1A1L3MBTL1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006124897-A2 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITION | LEXICON GENETICS INCORPORATED (US) | 2006-11-23 | — | — | WO | disclosed |