Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13039584 | 0.88 | CNR1 (0.36) | MGLLCNR1CNR2 | |
| SCHEMBL4403643 | 0.87 | CACNB4 (0.45) | MGLLPKMMEN1KMT2ACNR1 | |
| SCHEMBL3558149 | 0.86 | CNR1 (0.37) | CNR1CNR2 | |
| SCHEMBL12993541 | 0.84 | CNR1 (0.38) | ALDH1A1CNR1CNR2 | |
| SCHEMBL4403256 | 0.84 | CHRM1 (0.40) | CNR1CNR2 | |
| SCHEMBL3556587 | 0.83 | MGLL (0.52) | MGLLPKMMEN1KMT2ACYP2C9 | |
| SCHEMBL3557048 | 0.76 | ALOX5 (0.45) | ALDH1A1CNR1CNR2 | |
| SCHEMBL13593105 | 0.75 | MAT2A (0.41) | CNR1CNR2HTTSMN1; SMN2 | |
| SCHEMBL3551780 | 0.75 | MET (0.41) | ALDH1A1CNR1CNR2 | |
| SCHEMBL13593109 | 0.73 | CNR1 (0.50) | ALDH1A1LMNACNR1CNR2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006138657-A1 | BICYCLIC HETEROCYCLES AS CANNABINOID-1 RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-12-28 | — | — | WO | disclosed |