Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19100943 | 0.83 | ALDH1A1 (0.51) | ALDH1A1TP53MEN1KMT2ASYK | |
| SCHEMBL2221978 | 0.83 | AHR (0.55) | ALDH1A1TP53MEN1KMT2ASYK | |
| SCHEMBL1628253 | 0.83 | MEN1 (0.62) | ALDH1A1MEN1KMT2ASYKPOLB | |
| SCHEMBL5211841 | 0.82 | MEN1 (0.47) | ALDH1A1TP53MEN1KMT2ASYK | |
| SCHEMBL22056715 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TP53MEN1KMT2ASYK | |
| SCHEMBL7563419 | 0.82 | SMN1; SMN2 (0.49) | ALDH1A1TP53NPC1RAB9AMAPT | |
| SCHEMBL3518634 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TP53MEN1KMT2ASYK | |
| SCHEMBL46639 | 0.81 | MEN1 (0.53) | ALDH1A1MEN1KMT2APOLBTDP1 | |
| SCHEMBL30879313 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TP53MEN1KMT2ASYK | |
| SCHEMBL26930705 | 0.81 | POLB (0.58) | ALDH1A1TP53MEN1KMT2ASYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006076970-A | METHOD FOR PRODUCTION OF 4-CHLORO-2-(METHYLTHIO)PYRIMIDINES | AIR WATER CHEMICAL INC | 2006-03-23 | — | — | JP | disclosed |