Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.45 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4762536 | 0.81 | HTT (0.55) | MEN1KMT2AKDM4EPOLBAHR | |
| SCHEMBL27650617 | 0.81 | MEN1 (0.67) | MEN1KMT2AKDM4EKDM6BKDM4A | |
| SCHEMBL9152373 | 0.81 | RAB9A (0.48) | MEN1KMT2AKDM6BKDM4AKDM4D | |
| SCHEMBL16046321 | 0.81 | MEN1 (0.46) | MEN1KMT2AALDH1A1POLBTHRB | |
| SCHEMBL5824244 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1POLBTDP1 | |
| SCHEMBL2226205 | 0.80 | MEN1 (0.60) | MEN1KMT2AKDM4EKDM6BKDM4A | |
| SCHEMBL22056908 | 0.80 | MEN1 (0.51) | MEN1KMT2AKDM4EKDM6BKDM4A | |
| SCHEMBL3084614 | 0.80 | KDM4E (0.54) | MEN1KMT2AKDM4EKDM6BKDM4A | |
| Hydrochloric Acid SCHEMBL10559938 | 0.79 | MEN1 (0.58) | MEN1KMT2AKDM4EKDM6BKDM4A | |
| SCHEMBL2799992 | 0.79 | POLB (0.52) | MEN1KMT2AKDM4EKDM6BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114933567-B | Preparation method of 2-methylthio-4-pyrimidinone | 武汉工程大学 | 2023-07-11 | — | — | CN | claimed |
| CN-114933567-A | Preparation method of 2-methylthio-4-pyrimidone | 武汉工程大学 | 2022-08-23 | — | — | CN | claimed |
| CN-108707141-A | The preparation method of avanaphil | 苏州中联化学制药有限公司 | 2018-10-26 | — | — | CN | claimed |
| CN-108101853-A | A kind of synthetic method of the chloro- 2- methylthiopyrimidines -5- carboxylic acid, ethyl esters of high-purity 4- | 吴江信凯医药科技有限公司 | 2018-06-01 | — | — | CN | claimed |
| US-20250195535-A1 | PHARMACEUTICAL LIQUID COMPOSITIONS OF MELOXICAM | SLAYBACK PHARMA LLC (US) | 2025-06-19 | — | — | US | disclosed |
| US-12263176-B2 | Pharmaceutical liquid compositions of meloxicam | SLAYBACK PHARMA LLC (US) | 2025-04-01 | — | — | US | disclosed |
| CN-119707835-A | 2-Aminopyrimidine-5-carboxamide compounds and use thereof for the production of medicaments for the treatment and/or prophylaxis of cancer | 沈阳药科大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-119504571-A | Right-embedded alcohol or fenchyl alcohol ester derivatives of 2-hydroxy nicotinic acid and pharmaceutical application thereof | 苏州缘聚医药科技有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-114072411-B | Pyrimidine derivatives as Wee1 inhibitors | 微境生物医药科技(上海)有限公司 | 2024-05-24 | — | — | CN | disclosed |
| US-20240139204-A1 | PHARMACEUTICAL LIQUID COMPOSITIONS OF MELOXICAM | SLAYBACK PHARMA LLC (US) | 2024-05-02 | — | — | US | disclosed |
| CN-114933567-B | Preparation method of 2-methylthio-4-pyrimidinone | 武汉工程大学 | 2023-07-11 | — | — | CN | disclosed |
| CN-114933567-B | Preparation method of 2-methylthio-4-pyrimidinone | 武汉工程大学 | 2023-07-11 | — | — | CN | disclosed |
| US-20140023611-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. | 2014-01-23 | — | — | US | disclosed |
| US-20140023611-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. | 2014-01-23 | — | — | US | disclosed |
| CN-103265534-A | Method for preparing avanafil | SUZHOU MINGYUE MEDICAL TECHNOLOGY CO LTD | 2013-08-28 | — | — | CN | disclosed |
| CN-103254179-A | Preparation method of Avanafil | SUZHOU MINGRUI MEDICAL TECHNOLOGY CO LTD | 2013-08-21 | — | — | CN | disclosed |
| CN-103254180-A | Preparation method of Avanafil | SUZHOU MINGRUI MEDICAL TECHNOLOGY CO LTD | 2013-08-21 | — | — | CN | disclosed |
| WO-2012054110-A2 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-04-26 | — | — | WO | disclosed |
| WO-2012006475-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |
| US-7176310-B1 | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents | UCB SA (GB) | 2007-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250195535-A1 | PHARMACEUTICAL LIQUID COMPOSITIONS OF MELOXICAM | P2RY12, P2RY10, P2RY6 | MEN1 185/4885KMT2A 1169/4885KDM4E 1420/4885 |
| US-20140023611-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | SLC10A2, SLC34A2, SLC34A3 | MEN1 3183/4885KMT2A 4830/4885KDM4E 4411/4885 |
| US-12263176-B2 | Pharmaceutical liquid compositions of meloxicam | P2RY12, P2RY10, P2RY6 | MEN1 185/4885KMT2A 1169/4885KDM4E 1420/4885 |
| US-20240139204-A1 | PHARMACEUTICAL LIQUID COMPOSITIONS OF MELOXICAM | P2RY12, P2RY10, P2RY6 | MEN1 185/4885KMT2A 1169/4885KDM4E 1420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.