Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.59 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 2/20 | 0.42 |
| ▸ | ACACA | Q13085 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CRYAB | P02511 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 6/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5824299 | 0.88 | HSD11B1 (0.61) | HSD11B1ACHEHSD11B2ACLYACACA | |
| SCHEMBL30741399 | 0.82 | HSD11B1 (0.62) | HSD11B1ACHEHSD11B2ACLYACACA | |
| SCHEMBL31237297 | 0.81 | HSD11B1 (0.82) | HSD11B1ACHEACLYACACAMEN1 | |
| SCHEMBL5823474 | 0.80 | HSD11B1 (0.57) | HSD11B1ACHEHSD11B2ACLYACACA | |
| SCHEMBL5824245 | 0.80 | HSD11B1 (0.69) | HSD11B1ACHEHSD11B2ACLYACACA | |
| Cycloartenone SCHEMBL29504219 | 0.80 | HSD11B1 (0.61) | HSD11B1ACHEACLYACACAMEN1 | |
| SCHEMBL30020818 | 0.79 | HSD11B1 (0.70) | HSD11B1ACHEACLYACACAMEN1 | |
| SCHEMBL29934767 | 0.78 | HSD11B1 (0.77) | HSD11B1HSD11B2ACLYACACAMEN1 | |
| Mangiferonic Acid SCHEMBL30415919 | 0.77 | ACLY (0.70) | HSD11B1ACHEACLYACACAMEN1 | |
| Mangiferonic Acid SCHEMBL29873759 | 0.77 | ACLY (0.70) | HSD11B1ACHEACLYACACAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006131595-A | CARCINOGENESIS PREVENTING AGENT AND METHOD FOR PREPARING CYCLOARTANE-TYPE TRITERPENE COMPOUND | UNIV NIHON | 2006-05-25 | — | — | JP | disclosed |