Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.62 |
| ▸ | ACLY | P53396 | 2/20 | 0.44 |
| ▸ | ACACA | Q13085 | 2/20 | 0.44 |
| ▸ | CRYAB | P02511 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5824299 | 0.85 | HSD11B1 (0.61) | HSD11B1ACLYACACACRYABFNTA | |
| SCHEMBL31237297 | 0.83 | HSD11B1 (0.82) | HSD11B1ACLYACACACRYABMAPK1 | |
| Cycloartenone SCHEMBL29504219 | 0.82 | HSD11B1 (0.61) | HSD11B1ACLYACACAMAPK1PTPN11 | |
| SCHEMBL5822876 | 0.82 | HSD11B1 (0.59) | HSD11B1ACLYACACACRYABMAPK1 | |
| SCHEMBL29767002 | 0.82 | ACLY (0.63) | HSD11B1ACLYACACACRYABPTPN11 | |
| SCHEMBL30020818 | 0.81 | HSD11B1 (0.70) | HSD11B1ACLYACACACRYABMAPK1 | |
| SCHEMBL5824245 | 0.81 | HSD11B1 (0.69) | HSD11B1ACLYACACACRYABMAPK1 | |
| SCHEMBL29934767 | 0.80 | HSD11B1 (0.77) | HSD11B1ACLYACACAMAPK1PTPN11 | |
| Mangiferonic Acid SCHEMBL29873759 | 0.79 | ACLY (0.70) | HSD11B1ACLYACACAMAPK1PTPN11 | |
| Mangiferonic Acid SCHEMBL30415919 | 0.79 | ACLY (0.70) | HSD11B1ACLYACACAMAPK1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112739454-B | Improvements in or relating to organic compounds | 奇华顿股份有限公司 | 2024-01-09 | — | — | CN | disclosed |