Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.33 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30639420 | 0.84 | — | — | |
| SCHEMBL1696444 | 0.84 | ALDH1A1 (0.33) | POLBUSP2ALDH1A1TSHR | |
| SCHEMBL30166170 | 0.81 | NPC1 (0.39) | POLBUSP2ALDH1A1TSHR | |
| SCHEMBL9678617 | 0.80 | HSD17B10 (0.41) | CA2CA12CA1CA9CHKA | |
| SCHEMBL319864 | 0.79 | ALDH1A1 (0.41) | USP2ALDH1A1 | |
| SCHEMBL1821635 | 0.77 | CA2 (0.38) | CA2CA12CA1CA9CHKA | |
| SCHEMBL16343135 | 0.74 | RAB9A (0.49) | CA12CA1CA9POLBHSD17B10 | |
| SCHEMBL320334 | 0.74 | RAB9A (0.49) | CA12CA1CA9POLBHSD17B10 | |
| SCHEMBL30499311 | 0.74 | CYP1A2 (0.38) | CA2CA12CA9POLBHSD17B10 | |
| SCHEMBL19617740 | 0.74 | CHRNB2 (0.34) | CA2CA12CA1CA9CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060776-B2 | Monomers useful in the preparation of separation matrices | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2006-06-13 | — | — | US | disclosed |
| US-20050113539-A1 | Crosslinked, water insoluble matrix; electrophoresis membranes | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2005-05-26 | — | — | US | disclosed |
| WO-2003055923-A1 | NOVEL MONOMERS USEFUL IN THE PREPARATION OF SEPARATION MATRICES | AMERSHAM BIOSCIENCES AB (SE) | 2003-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113539-A1 | Crosslinked, water insoluble matrix; electrophoresis membranes | H1-0, H1-4, H1-2 | CA2 3075/4885CA12 3166/4885CA1 1624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.