Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.57 |
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5829495 | 0.88 | RAB9A (0.49) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL5669641 | 0.86 | POLB (0.54) | NPC1RAB9ATP53KMT2AKCNK9 | |
| SCHEMBL5829094 | 0.85 | KCNK3 (0.48) | NPC1RAB9ASMN1; SMN2KMT2AKCNK3 | |
| SCHEMBL14498667 | 0.84 | TP53 (0.54) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL5829149 | 0.83 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL10988061 | 0.83 | ALDH1A1 (0.45) | RAB9ASMN1; SMN2KMT2AALDH1A1PKM | |
| SCHEMBL5829255 | 0.82 | KCNK3 (0.58) | NPC1RAB9ATP53KMT2AKCNK9 | |
| SCHEMBL5829567 | 0.82 | MEN1 (0.50) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL10986870 | 0.82 | ALDH1A1 (0.44) | RAB9ASMN1; SMN2KMT2AALDH1A1PKM | |
| SCHEMBL1537861 | 0.80 | IDO1 (0.54) | NPC1RAB9AALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420292-B1 | Stabilizers for use in substantially light-insensitive thermographic recording materials. | AGFA GEVAERT (BE) | 2006-06-28 | — | — | EP | disclosed |
| US-6908731-B2 | Stabilizers for use in substantially light-insensitive thermographic recording materials | AGFA-GEVAERT (BE) | 2005-06-21 | — | — | US | disclosed |