Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.53 |
| ▸ | RAB9A | P51151 | 10/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5669641 | 0.87 | POLB (0.54) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL5829094 | 0.84 | KCNK3 (0.48) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL5829495 | 0.84 | RAB9A (0.49) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL5828107 | 0.83 | NPC1 (0.57) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL5829255 | 0.83 | KCNK3 (0.58) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL5829567 | 0.81 | MEN1 (0.50) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL14498648 | 0.80 | TSHR (0.46) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13297735 | 0.80 | POLB (0.41) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL10530651 | 0.80 | MEN1 (0.51) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL7100985 | 0.80 | P2RX1 (0.51) | NPC1RAB9AKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420292-B1 | Stabilizers for use in substantially light-insensitive thermographic recording materials. | AGFA GEVAERT (BE) | 2006-06-28 | — | — | EP | disclosed |
| US-6908731-B2 | Stabilizers for use in substantially light-insensitive thermographic recording materials | AGFA-GEVAERT (BE) | 2005-06-21 | — | — | US | disclosed |