Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5828617 | 0.88 | L3MBTL1 (0.38) | L3MBTL1MAPTNPC1RAB9AAGTR2 | |
| SCHEMBL5828966 | 0.86 | HSD17B10 (0.48) | GAACYP2C9CYP2C19L3MBTL1RECQL | |
| SCHEMBL5167210 | 0.84 | PPARG (0.39) | GAACYP2C9CYP2C19L3MBTL1RECQL | |
| SCHEMBL5170081 | 0.81 | GAA (0.42) | GAACYP2C9CYP2C19L3MBTL1RECQL | |
| SCHEMBL5167607 | 0.74 | GAA (0.44) | GAACYP2C9CYP2C19L3MBTL1RECQL | |
| SCHEMBL5169425 | 0.73 | MAPT (0.44) | GAACYP2C9CYP2C19L3MBTL1KDM4E | |
| SCHEMBL11093075 | 0.72 | NPC1 (0.48) | GAACYP2C9CYP2C19L3MBTL1RECQL | |
| SCHEMBL8552490 | 0.71 | ALDH1A1 (0.42) | GAACYP2C9CYP2C19RECQLPOLB | |
| SCHEMBL17294909 | 0.70 | GAA (0.44) | GAACYP2C9CYP2C19L3MBTL1RECQL | |
| SCHEMBL17304924 | 0.70 | GAA (0.44) | GAACYP2C9CYP2C19L3MBTL1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084244-B2 | Conformationally constrained backbone cyclized peptide analogs | DEVELOGEN ISRAEL LTD. (IL) | 2006-08-01 | — | — | US | disclosed |
| US-20030144186-A1 | Conformationally constrained backbone cyclized peptide analogs | DEVELOGEN ISRAEL LTD. (IL) | 2003-07-31 | — | — | US | disclosed |
| US-6407059-B1 | SOMATOSTATIN-TYPE DRUG | PEPTOR LIMITED (IL) | 2002-06-18 | — | — | US | disclosed |
| US-6265375-B1 | Conformationally constrained backbone cyclized peptide analogs | YISSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY (IL) | 2001-07-24 | — | — | US | disclosed |
| US-5883293-A | SOMATOSTATIN CONPOUNDS | PEPTOR LTD. (IL) | 1999-03-16 | — | — | US | disclosed |
| US-5874529-A | BRADYKININ ANTAGONIST | PEPTOR LTD. (IL) | 1999-02-23 | — | — | US | disclosed |
| US-5811392-A | BRADYKININ ANTAGONISTS; SOMATOSTATIN ANALOGS | YISSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY (IL) | 1998-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144186-A1 | Conformationally constrained backbone cyclized peptide analogs | VIP, BDKRB1, BDKRB2 | GAA 3749/4885CYP2C9 4476/4885CYP2C19 3991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.