Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | LAP3 | P28838 | 1/20 | 0.47 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153568 | 0.91 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1SLC15A1ABCB1 | |
| SCHEMBL22311019 | 0.91 | SLC15A1 (0.50) | ALDH1A1MAPK1L3MBTL1SLC15A1ABCB1 | |
| SCHEMBL25622569 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1SLC15A1ABCB1 | |
| SCHEMBL10779380 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1SLC15A1ABCB1 | |
| SCHEMBL31448302 | 0.85 | TRPA1 (0.53) | ALDH1A1L3MBTL1ABCB1TRPA1TRPV1 | |
| SCHEMBL10774468 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1SLC15A1ABCB1 | |
| SCHEMBL15180189 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1SLC15A1ABCB1 | |
| SCHEMBL12268225 | 0.85 | TRPA1 (0.53) | ALDH1A1L3MBTL1ABCB1TRPA1TRPV1 | |
| SCHEMBL5837006 | 0.85 | TRPA1 (0.53) | ALDH1A1L3MBTL1ABCB1TRPA1TRPV1 | |
| SCHEMBL28002144 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1SLC15A1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39333-E1 | Process for the preparation of 5-hydroxy-3-oxopentanoic acid derivatives | KANEKA CORPORATION (JP) | 2006-10-10 | — | — | US | disclosed |
| EP-1104750-B1 | PROCESSES FOR THE PREPARATION OF 5-HYDROXY-3-OXOPENTANOIC ACID DERIVATIVES | KANEKA CORP (JP) | 2004-04-14 | — | — | EP | disclosed |
| US-6340767-B1 | REACTION OF LITHIUM AMIDE WITH ACETIC ACID ESTER AND HYDROXY PROPIONIC ACID | KANEKA CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-1104750-A1 | PROCESSES FOR THE PREPARATION OF 5-HYDROXY-3-OXOPENTANOIC ACID DERIVATIVES | KANEKA CORPORATION (JP) | 2001-06-06 | — | — | EP | disclosed |