Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | PPID | Q08752 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31448302 | 1.00 | TRPA1 (0.53) | TRPA1MMP8ALDH1A1TSHRSRR | |
| SCHEMBL12268225 | 1.00 | TRPA1 (0.53) | TRPA1MMP8ALDH1A1TSHRSRR | |
| SCHEMBL27683839 | 0.87 | TRPA1 (0.50) | TRPA1MMP8ALDH1A1SRRABCB1 | |
| SCHEMBL11847679 | 0.85 | F10 (0.47) | ALDH1A1TSHRMEN1NPC1KMT2A | |
| SCHEMBL18065659 | 0.85 | MMP8 (0.53) | MMP8ALDH1A1TSHRSRRPPID | |
| SCHEMBL5829150 | 0.85 | ALDH1A1 (0.58) | TRPA1ALDH1A1SRRABCB1TRPV1 | |
| SCHEMBL12446348 | 0.83 | MMP8 (0.51) | MMP8ALDH1A1TSHRSRRPPID | |
| SCHEMBL7633821 | 0.83 | ABCB1 (0.57) | TRPA1ALDH1A1SRRABCB1TRPV1 | |
| SCHEMBL1645938 | 0.82 | EPHX1 (0.50) | MMP8ALDH1A1TSHRSRRPPID | |
| SCHEMBL5533332 | 0.82 | TRPA1 (0.59) | TRPA1ALDH1A1TSHRSRRABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119614529-A | Short-chain dehydrogenase, engineering bacteria and application thereof in asymmetric reduction of potential chiral carbonyl compounds | 杭州文德阶生物科技有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-118344296-A | Process for the stereoselective preparation of chiral 2- [ (hetero) aralkylthio ] pyrimidines and products obtainable therefrom | 坎塞拉有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-112218853-B | Process for the stereoselective preparation of chiral 2- [ (hetero) aralkylthio ] pyrimidines and products obtainable therefrom | 坎塞拉有限公司 | 2024-07-02 | — | — | CN | disclosed |
| US-20230373999-A1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2023-11-23 | — | — | US | disclosed |
| US-20210387960-A1 | NRF2 ACTIVATOR | BIOGEN MA INC. | 2021-12-16 | — | — | US | disclosed |
| EP-3715339-B1 | PREPARATION METHOD OF BETA-HYDROXYCARBOXYLIC ACID ESTER | SHENYANG GOLD JYOUKI TECH CO LTD (CN) | 2021-09-29 | — | — | EP | disclosed |
| EP-3715339-B1 | PREPARATION METHOD OF BETA-HYDROXYCARBOXYLIC ACID ESTER | SHENYANG GOLD JYOUKI TECH CO LTD (CN) | 2021-09-29 | — | — | EP | disclosed |
| US-11028039-B2 | Method for preparing a β-hydroxycarboxylic acid ester | Shenyang Gold Jyouki Technology Co., Ltd (CN) | 2021-06-08 | — | — | US | disclosed |
| US-11028039-B2 | Method for preparing a β-hydroxycarboxylic acid ester | Shenyang Gold Jyouki Technology Co., Ltd (CN) | 2021-06-08 | — | — | US | disclosed |
| US-20200308093-A1 | METHOD FOR PREPARING A β -HYDROXYCARBOXYLIC ACID ESTER | Shenyang Gold Jyouki Technology Co., Ltd (CN) | 2020-10-01 | — | — | US | disclosed |
| EP-3715339-A1 | PREPARATION METHOD OF BETA-HYDROXYCARBOXYLIC ACID ESTER | Shenyang Gold Jyouki Technology Co., Ltd (CN) | 2020-09-30 | — | — | EP | disclosed |
| US-10689377-B2 | KRas G12C inhibitors | Mirati Therapeutics, Inc. (US) | 2020-06-23 | — | — | US | disclosed |
| US-20190144444-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. | 2019-05-16 | — | — | US | disclosed |
| WO-2018140738-A1 | NRF 2 ACTIVATOR | BIOGEN MA INC. (US) | 2018-08-02 | — | — | WO | disclosed |
| US-7109004-B2 | Process for reducing an alpha-keto ester | MERCK & CO., INC. (US) | 2006-09-19 | — | — | US | disclosed |
| EP-1176135-B1 | Process for producing optically active alcohol | TAKASAGO PERFUMERY CO LTD (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-20040101937-A1 | Process for reducing an alpha-keto ester | MERCK & CO., INC. | 2004-05-27 | — | — | US | disclosed |
| US-6492545-B2 | Process for producing optically active alcohol | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-12-10 | — | — | US | disclosed |
| US-20020035283-A1 | Process for producing optically active alcohol | TAKASAGO INTERNATIONAL CORPORATION | 2002-03-21 | — | — | US | disclosed |
| EP-1176135-A1 | Process for producing optically active alcohol | Takasago International Corporation (JP) | 2002-01-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190144444-A1 | KRAS G12C INHIBITORS | KRAS, NRAS, HRAS | TRPA1 4503/4885MMP8 1835/4885ALDH1A1 3370/4885 |
| US-20210387960-A1 | NRF2 ACTIVATOR | NFE2L2, NFE2, KEAP1 | TRPA1 1518/4885MMP8 1612/4885ALDH1A1 823/4885 |
| US-11028039-B2 | Method for preparing a β-hydroxycarboxylic acid ester | HAO2, HAAO, MCCC2 | TRPA1 3232/4885MMP8 164/4885ALDH1A1 304/4885 |
| US-20200308093-A1 | METHOD FOR PREPARING A β -HYDROXYCARBOXYLIC ACID ESTER | HAO2, HAAO, ADH1A | TRPA1 3153/4885MMP8 97/4885ALDH1A1 148/4885 |
| US-10689377-B2 | KRas G12C inhibitors | KRAS, NRAS, HRAS | TRPA1 4503/4885MMP8 1835/4885ALDH1A1 3370/4885 |
| US-20020035283-A1 | Process for producing optically active alcohol | ADH1A, ADH5, ADH1C | TRPA1 4130/4885MMP8 4824/4885ALDH1A1 38/4885 |
| US-20230373999-A1 | KRAS G12C INHIBITORS | KRAS, NRAS, HRAS | TRPA1 4503/4885MMP8 1835/4885ALDH1A1 3370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.